Why the study?
The study was conducted to evaluate the clinical and hemodynamic effects of S-amlodipine in patients with arterial hypertension associated with coronary artery disease and preserved LV systolic function.
Does S-amlodipine improve hemodynamics and LV diastolic function in patients with arterial hypertension and coronary artery disease?
Does S-amlodipine improve hemodynamics and LV diastolic function in patients with arterial hypertension and coronary artery disease?
S-amlodipine improves LV diastolic function and hemodynamics in patients with hypertension and coronary artery disease with preserved systolic function.
May support S-amlodipine use in hypertensive CAD with preserved EF; hypothesis-generating and requires randomized confirmation.
OBJECTIVE: The aim: Study of the clinical and hemodynamic effects of S-amlodipine in patients with arterial hypertension associated with coronary artery disease, in individuals with preserved LV systolic function. PATIENTS AND METHODS: Materials and methods: The study includes 51 patients with arterial hypertension associated with coronary artery disease, who were treated with S-amlodipine. RESULTS: Results: This study shows the high clinical effectiveness of the use of S-amlodipine in patients with arterial hypertension associated with coronary artery disease. We reveal that treatment of hypertensive patients with coronary artery disease with S-amlodipine leads to improvement of LV diastolic dysfunction, bringing it closer to normal values. CONCLUSION: Conclusions: Clinical effectiveness was associated with positive changes in hemodynamics, and was expressed in the normalization of the left ventricle diastolic function parameters, about which indirectly indicates decreasing of end-diastolic pressure.
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Чопей et al. (2023) studied Medical diagnosis (n=50). ChatGPT-3.5 vs. Medical professionals was evaluated on Diagnostic accuracy in the initial phase.
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