Key result
Higher serum lipopolysaccharide-binding protein levels were independently and positively associated with increased arterial stiffness (β = 0.135, p = 0.026) in patients with type 2 diabetes.
Why the study?
Are serum lipopolysaccharide-binding protein levels associated with arterial stiffness in patients with type 2 diabetes?
Cross-Sectional (n=196)
No
Are serum lipopolysaccharide-binding protein levels associated with arterial stiffness in patients with type 2 diabetes?
Effect estimate: β = 0.135
p-value: p=0.026
Serum LBP levels are independently associated with arterial stiffness in patients with type 2 diabetes, particularly in men, suggesting a link between innate immunity and vascular complications.
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Should not yet change practice in T2D; hypothesis-generating for sex-specific LBP-vascular links.
Sakura et al. (2017) conducted a cross-sectional in Type 2 diabetes (n=196). Serum lipopolysaccharide-binding protein (LBP) levels was evaluated on Arterial stiffness assessed by aortic pulse wave velocity (PWV) (β = 0.135, p=0.026). Higher serum lipopolysaccharide-binding protein levels were independently and positively associated with increased arterial stiffness (β = 0.135, p = 0.026) in patients with type 2 diabetes.
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