Key result
Community care significantly reduced systolic blood pressure (WMD -3.54 mmHg; 95% CI -4.73 to -2.35; P<0.001), diastolic blood pressure, LDL, and triglycerides compared to routine care.
Why the study?
Evidence on the efficacy of community care in reducing cardiovascular disease risk factors remains fragmented and inconsistent due to heterogeneity in intervention designs and population characteristics.
Does community care reduce cardiovascular disease risk factors in patients with at least one CVD risk factor?
Meta-Analysis (n=10,749)
Does community care reduce cardiovascular disease risk factors in patients with at least one CVD risk factor?
Mean Difference: -3.54 (95% CI -4.73–-2.35)
p-value: p=< 0.001
Community care interventions including health education and follow-up effectively improve blood pressure, lipid profiles, and smoking cessation rates for primary CVD prevention.
Supports community care integration for hypertension and lipid management; confirms benefits across aggregated trials.
Rationale Cardiovascular disease (CVD) remains a leading global cause of morbidity and mortality, with hypertension, dyslipidemia, and smoking as key modifiable risk factors. While pharmacological interventions are effective, their accessibility in resource‐limited settings highlights the need for scalable nonpharmacological strategies. Community care has emerged as a potential solution, yet evidence on its efficacy in reducing CVD risk factors remains fragmented and inconsistent due to heterogeneity in intervention designs and population characteristics. Aim To evaluate the effectiveness of community care in reducing CVD risk factors (blood pressure, lipids, smoking) and explore geographical heterogeneity. Methods Fifteen RCTs ( n = 10,749) from PubMed, Embase, Cochrane Library, and Web of Science (up to January 2025) were included. Participants had ≥ 1 CVD risk factor and received community nursing (health education, follow‐up) versus routine care. Random‐effects models in Stata 17.0 analysed outcomes (SBP, DBP, HDL, LDL, TG, smoking). Subgroups assessed sample size, region, duration, and quality. Results Community care significantly reduced SBP (WMD = − 3.54 mmHg, 95% CI: − 4.73 to −2.35; p < 0.001), DBP (WMD = − 1.47 mmHg, −1.94 to −0.99; p < 0.001), LDL ( − 5.11 mg/dL; p < 0.001), and TG ( − 4.21 mg/dL; p = 0.024), with lower smoking persistence (RR = 0.949; p = 0.033). No HDL improvement was observed (WMD = 1.26 mg/dL; p = 0.323). Subgroups showed stronger TG reduction in developing countries (P interaction = 0.010) and greater smoking cessation efficacy in developed nations (P interaction = 0.085). Conclusion Community care effectively lowers blood pressure, LDL, TG, and smoking persistence, supporting its role in primary CVD prevention. Limited HDL impact and regional variations necessitate tailored interventions and further research on HDL functionality.
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Luo et al. (2025) conducted a meta-analysis in Cardiovascular disease risk factors (n=10,749). Community care vs. Routine care was evaluated on Systolic blood pressure (SBP) (WMD -3.54, 95% CI -4.73 to -2.35, p=< 0.001). Community care significantly reduced systolic blood pressure (WMD -3.54 mmHg; 95% CI -4.73 to -2.35; P<0.001), diastolic blood pressure, LDL, and triglycerides compared to routine care.
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