Key result
A bedside monitor (Coagucheck Plus) showed substantial disagreement with laboratory assays for aPTT and INR during treatment with various classic and novel anticoagulants (P<0.001).
Why the study?
Does bedside monitoring of aPTT and INR agree with laboratory assays in patients treated with classic and novel anticoagulants?
Population
Patients receiving warfarin, heparin, or novel anticoagulants
Comparison
Bedside monitor measurement of activated partial… vs Laboratory assay measurement of aPTT and INR
Design
Other
Authors
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May warrant laboratory confirmation of bedside aPTT/INR results; leaves open device accuracy across novel anticoagulants.
Observational
Does bedside monitoring of aPTT and INR agree with laboratory assays in patients treated with classic and novel anticoagulants?
p-value: p=<0.001
Bedside monitors for aPTT and INR may show substantial, anticoagulant-dependent disagreement with laboratory assays, particularly for novel anticoagulants.
Kemme et al. (2001) conducted an observational in Treatment with various anticoagulants. Bedside monitor (Coagucheck Plus) vs. Laboratory assay was evaluated on Disagreement between bedside and laboratory aPTT and INR (p=<0.001). A bedside monitor (Coagucheck Plus) showed substantial disagreement with laboratory assays for aPTT and INR during treatment with various classic and novel anticoagulants (P<0.001).
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