Key result
A triad arrangement of an arteriole accompanied by two venules protected the arteriole during cardiac contraction, resulting in a 4% area increase compared to a 45% reduction in unaccompanied vessels.
Population
Computational model of intramyocardial coronary vessels
Comparison
Triad arrangement vs Unaccompanied arteriole and unaccompanied venule
Design
Preclinical
Authors
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Findings in animal models warrant no change in coronary disease care; extends microvascular anatomy knowledge and leaves human relevance open.
Absolute Event Rate: 4% vs -45%
The triad arrangement of intramyocardial coronary vessels protects arterioles from compression during cardiac contraction, attenuating the increase in coronary resistance.
Vis et al. (1997) studied Coronary physiology. Triad arrangement of intramyocardial coronary vessels (arteriole accompanied by two venules) vs. Unaccompanied arteriole and unaccompanied venule was evaluated on Change in arteriolar cross-sectional area during contraction with 14% cardiac muscle shortening. A triad arrangement of an arteriole accompanied by two venules protected the arteriole during cardiac contraction, resulting in a 4% area increase compared to a 45% reduction in unaccompanied vessels.
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