Key result
Primary pulmonary hypertension demonstrated a variable clinical course, with progressive hemodynamic deterioration in 3 of 5 patients undergoing repeated catheterization, unaffected by any therapy.
Population
16 patients with primary pulmonary hypertension
Design
Case_series
Follow-up
1 to 4 years
Authors
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Suggests need for close monitoring in primary pulmonary hypertension; leaves open effective therapies pending controlled studies.
Observational (n=16)
Primary pulmonary hypertension has a variable clinical course characterized by progressive hemodynamic deterioration that appears unaffected by therapies such as long-term anticoagulation.
Sleeper et al. (1962) conducted an observational in Primary pulmonary hypertension (n=16). Primary pulmonary hypertension was evaluated on Pulmonary hemodynamics and arterial oxygen saturation. Primary pulmonary hypertension demonstrated a variable clinical course, with progressive hemodynamic deterioration in 3 of 5 patients undergoing repeated catheterization, unaffected by any therapy.
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