contrasted the effects of depolarizing muscle relaxants with those of competitive blocking agents resembling tubocurarine. Decamethonium caused potentiation of twitches with repetitive discharge, whereas competitive antagonists did not have this effect. However, Riker & Wescoe (1951) reported that gallamine, in doses smaller than, and up to, the minimal effective curariform dose, may produce a slight potentiation of the muscle response to indirect stimulation. A similar observation is reported here on rat phrenic nerve-diaphragm preparations together with an examination of the possible mechanism.
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Jones et al. (1965) studied this question.
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