Key result
In simulated and in-vitro models of planar artery bifurcations, low flow velocity zones and low shear stress values were located in the outer walls, with a critical bifurcation angle of 60°-90° being most prone to vascular disease.
Computational and experimental models demonstrate that specific bifurcation angles create low shear stress zones on outer walls, increasing the hemodynamic risk for atherosclerosis.
No takes yet. Share an insight, caveat, or question.
Provides physical maps of stenosis-prone vessel regions in models; leaves open clinical translation for atherosclerosis prediction.
Otero-Cacho et al. (2018) studied Vascular disease / Atherosclerosis. Bifurcation angle was evaluated on Low velocity areas and wall shear stress. In simulated and in-vitro models of planar artery bifurcations, low flow velocity zones and low shear stress values were located in the outer walls, with a critical bifurcation angle of 60°-90° being most prone to vascular disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: