Key result
Surgical removal of an adrenal neuroblastoma in a child with dilated cardiomyopathy led to progressive and complete normalization of cardiac function.
Why the study?
Does surgical removal of a catecholamine-secreting neuroblastoma improve cardiac function in a child with dilated cardiomyopathy?
Case Report (n=1)
Does surgical removal of a catecholamine-secreting neuroblastoma improve cardiac function in a child with dilated cardiomyopathy?
Surgical removal of a catecholamine-secreting neuroblastoma can lead to complete reversal of dilated cardiomyopathy in children.
Supports neuroblastoma resection as reversible cause of pediatric cardiomyopathy; hypothesis-generating and should not yet change practice.
Reported is a child with dilated cardiomyopathy, in whom medical therapy resulted in a mild improvement of cardiac function. Metabolic studies suggested the presence of a catecholamine-secreting tumour; and an adrenal neuroblastoma was identified and surgically removed. Following surgery, there was progressive and complete normalization of cardiac function. Although very rare, neurogenic tumours may be involved in the development of a dilated cardiomyopathy in the infant and child.
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Rosti et al. (1999) conducted a case report in Dilated cardiomyopathy (n=1). Surgical removal of adrenal neuroblastoma was evaluated on Cardiac function. Surgical removal of an adrenal neuroblastoma in a child with dilated cardiomyopathy led to progressive and complete normalization of cardiac function.
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