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August 1, 1998The Journal of Clinical Endocrinology & Metabolism

Identification of Novel High Molecular Weight Insulin-Like Growth Factor-Binding Protein-3 Association Proteins in Human Serum1

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Key result

In human serum, IGFBP-3 specifically binds to at least three novel high-affinity association proteins with molecular masses of 70, 100, and 150 kDa, which are distinct from the acid-labile subunit.

Authors

PCPaulo Ferrez Collett‐SolbergUniversidade do Estado do Rio de JaneiroSNSteven E. NunnChildren's Hospital of PhiladelphiaTGTara Beers GibsonChildren's Hospital of Philadelphia

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Overview

Does not yet inform clinical IGF assessment; leaves open the physiologic roles of these novel IGFBP-3 binding proteins.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Collett‐Solberg et al. (1998) studied this question. In human serum, IGFBP-3 specifically binds to at least three novel high-affinity association proteins with molecular masses of 70, 100, and 150 kDa, which are distinct from the acid-labile subunit.

synapsesocial.com/papers/6a9422313fda5c29338c12e5https://doi.org/10.1210/jcem.83.8.5053
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Also Consider

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  4. 4THE ROLE OF THE INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS AND THE IGFBP PROTEASES IN MODULATING IGF ACTION1996 · 229 citations
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