April 1, 1995Journal of Endocrinology

Proteins in Tissue Extracts Which Bind Insulin-Like Growth Factor Binding Protein-3 (Igfbp-3)

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Population

Sheep and rat tissues

Design

Preclinical

Authors

SHS. HodgkinsonUniversität Ulm PFP. J. FowkeAgResearch NSN. Al Somai

Discussion

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Implication

No immediate clinical implications from these animal data; leaves open characterization of human IGFBP-3 binding proteins in muscle.

Structured PICO

Population

Sheep and rat tissues (muscle, pancreas, pituitary, liver, kidney, spleen, intestine, adrenal, brain, mammary, uterus, ovary, and plasma)

Intervention

Ligand blot analysis using radioiodinated recombinant human non-glycosylated IGFBP-3

Outcome

Identification and structural characterization of IGFBP-3 binding proteins

Identified novel tissue-specific proteins in sheep and rat extracts that specifically bind IGFBP-3, which may play a role in modulating IGF activity at the cellular level.

Cite This Study

Hodgkinson et al. (1995) studied this question.

synapsesocial.com/papers/6a96eaa01f16343146bb98df https://doi.org/10.1677/joe.0.145r001

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Proteins in Tissue Extracts Which Bind Insulin-Like Growth Factor Binding Protein-3 (Igfbp-3)

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Proteins in Tissue Extracts Which Bind Insulin-Like Growth Factor Binding Protein-3 (Igfbp-3)

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider