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October 28, 2016Biomarkers

Elevated plasma levels of MR-proADM determined 24 hours after diagnosis of cardiogenic shock predicted in-hospital mortality in patients with acute myocardial infarction (overall mortality 36%).

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Why the study?

Does the plasma level of MR-proADM predict cardiovascular death in patients with acute myocardial infarction complicated by cardiogenic shock?

Population

47 consecutive patients with acute myocardial infarction complicated by cardiogenic shock who underwent…

Design

Cohort

Follow-up

in-hospital

Key result

Elevated plasma levels of MR-proADM determined 24 hours after diagnosis of cardiogenic shock predicted in-hospital mortality in patients with acute myocardial infarction (overall mortality 36%).

Authors

KSKarolina SupełMKMichał KacprzakMZMarzenna Zielińska

Discussion

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Overview

MR-proADM may refine early mortality risk assessment in AMI shock; leaves open validation and incremental utility over existing scores.

Study Design

Type

Observational (n=47)

Structured PICO

Does the plasma level of MR-proADM predict cardiovascular death in patients with acute myocardial infarction complicated by cardiogenic shock?

P
Population
47 consecutive patients with acute myocardial infarction complicated by cardiogenic shock who underwent successful percutaneous coronary intervention.
E
Exposure
Measurement of plasma levels of midregional (MR)-proadrenomedullin (MR-proADM) 24 hours after diagnosis of cardiogenic shock.
O
Outcome
Cardiovascular death (in-hospital mortality)hard clinical

Elevated MR-proADM levels measured 24 hours after cardiogenic shock diagnosis may serve as a prognostic biomarker for in-hospital mortality in patients with AMI undergoing successful PCI.

Cite This Study

Supeł et al. (2016) conducted an observational in Acute myocardial infarction complicated by cardiogenic shock (n=47). Elevated plasma level of MR-proADM was evaluated on Cardiovascular death. Elevated plasma levels of MR-proADM determined 24 hours after diagnosis of cardiogenic shock predicted in-hospital mortality in patients with acute myocardial infarction (overall mortality 36%).

synapsesocial.com/papers/6a94235a3fda5c29338c133ahttps://doi.org/10.1080/1354750x.2016.1252962
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Also Consider

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  4. 4MR‐proADM as a Prognostic Marker in Patients With ST‐Segment–Elevation Myocardial Infarction—DANAMI‐3 (a Danish Study of Optimal Acute Treatment of Patients With STEMI) Substudy2018 · 25 citations
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