Key result
Acute myocardial infarction was associated with a peak plasma adrenomedullin concentration of 14.0 pmol/l at 24 hours, compared to 5.0 pmol/l in normal subjects.
Why the study?
Are plasma adrenomedullin levels increased in patients with acute myocardial infarction and do they correlate with clinical severity?
Population
31 patients with acute myocardial infarction and 44 normal subjects
Design
Cohort
Follow-up
four weeks
Authors
Loading...
Elevated adrenomedullin in acute MI should not change practice; leaves open its prognostic value or therapeutic targeting.
Observational (n=75)
Are plasma adrenomedullin levels increased in patients with acute myocardial infarction and do they correlate with clinical severity?
Absolute Event Rate: 14% vs 5%
Plasma adrenomedullin concentrations increase in the acute phase of myocardial infarction in proportion to clinical severity, suggesting it may play an important role in the pathophysiology of myocardial infarction.
Miyao et al. (1998) conducted an observational in Acute myocardial infarction (n=75). Acute myocardial infarction vs. Normal subjects was evaluated on Peak plasma adrenomedullin concentration (pmol/l). Acute myocardial infarction was associated with a peak plasma adrenomedullin concentration of 14.0 pmol/l at 24 hours, compared to 5.0 pmol/l in normal subjects.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: