Why the study?
Are plasma levels of adrenomedullin elevated in patients with cardiovascular, respiratory, hepatic, and renal disorders compared to healthy controls?
Population
58 male subjects, including 8 with essential hypertension, 12 with heart failure, 10 with ascites due to…
Design
Cross-sectional
Authors
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Adrenomedullin elevation was associated with multiple chronic diseases; hypothesis-generating for compensatory role or biomarker utility.
Are plasma levels of adrenomedullin elevated in patients with cardiovascular, respiratory, hepatic, and renal disorders compared to healthy controls?
Plasma adrenomedullin levels are elevated across a variety of cardiovascular, respiratory, hepatic, and renal diseases, suggesting it may play a compensatory vasodilatory role in these conditions.
Cheung et al. (1997) studied this question.
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