Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 15, 2002American Journal of Health-System Pharmacy

Cost of venous thromboembolism following major orthopedic surgery in hospitalized patients

View Full Paper
Ask AI
Bookmark
Share

Key result

Clinical VTE following major orthopedic surgery was associated with significantly higher mean inpatient costs ($17,114 for DVT only and $18,521 for PE vs $9,345 for no VTE; p<0.0001).

Why the study?

Does the development of VTE increase hospital length of stay and inpatient costs in patients undergoing major orthopedic surgery?

Population

Hospitalized patients who underwent total hip or knee replacement surgery or hip-fracture repair at 220 U.S…

Comparison

Development of clinical venous thromboembolism… vs No secondary diagnosis of VTE.

Design

Cohort

Follow-up

In-hospital

Authors

DODaniel A. OllendorfInstitute for Clinical and Economic ReviewMVMontserrat Vera‐LlonchIonis Pharmaceuticals (United States)GOGerry OsterPolicy Analysis (United States)

Discussion

Loading...

Member takes

Implication

VTE prophylaxis may curb orthopedic surgery costs; extends observational cost data but leaves open causal prevention benefits.

Study Design

Type

Cohort

Multicenter

Yes

Structured PICO

Does the development of VTE increase hospital length of stay and inpatient costs in patients undergoing major orthopedic surgery?

P
Population
Hospitalized patients who underwent total hip or knee replacement surgery or hip-fracture repair at 220 U.S. acute care hospitals between January 1998 and June 1999.
E
Exposure
Development of clinical venous thromboembolism (VTE), specifically deep vein thrombosis (DVT) without pulmonary embolism (PE) or PE with or without DVT.
C
Comparator
No secondary diagnosis of VTE.
O
Outcome
Length of hospital stay, use of intensive care services, and costs of inpatient care.

Main Result

Absolute Event Rate: 17114% vs 9345%

p-value: p=<0.0001

Development of VTE after major orthopedic surgery significantly increases hospital length of stay and nearly doubles inpatient costs.

Cite This Study

Ollendorf et al. (2002) conducted a cohort in Hospitalized patients after major orthopedic surgery. Clinical venous thromboembolism (VTE) vs. No VTE was evaluated on Mean total costs of inpatient care (p=<0.0001). Clinical VTE following major orthopedic surgery was associated with significantly higher mean inpatient costs ($17,114 for DVT only and $18,521 for PE vs $9,345 for no VTE; p<0.0001).

synapsesocial.com/papers/6a9424141e998d99dafeebc9https://doi.org/10.1093/ajhp/59.18.1750

Topics

Pulmonary embolism
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Economic Consequences of Venous Thromboembolism Following Major Orthopedic Surgery2004 · 56 citations
  2. 2The Incremental Cost of Inpatient Venous Thromboembolism After Hip Fracture Surgery2020 · 18 citations
  3. 3Venous thromboembolism following major orthopedic surgery: Review of epidemiology and economics2001 · 59 citations
  4. 4Burden of Deep Vein Thrombosis in the Outpatient Setting Following Major Orthopedic Surgery2008 · 21 citations
  5. 5Impact of postoperative venous thromboembolism on Medicare recipients undergoing total hip replacement or total knee replacement surgery2010 · 30 citations