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July 9, 2008Annals of Pharmacotherapy

Burden of Deep Vein Thrombosis in the Outpatient Setting Following Major Orthopedic Surgery

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Key result

Development of DVT within one month after major orthopedic surgery was associated with a 22% and 74% increase in outpatient and emergency department visits, respectively, and over $2000 in added costs.

Why the study?

Does the development of DVT following major orthopedic surgery increase healthcare costs and resource utilization in adult patients?

Population

32,899 patients 18 years of age or older with a record of major orthopedic surgery from the PharMetrics…

Comparison

Development of deep vein thrombosis during the… vs No development of DVT during the first month…

Design

Cohort

Follow-up

6 months postdischarge

Authors

ENEdith A. NutescuVascular MedicineASAndrew F. ShorrMedStar Washington Hospital CenterEFEileen FarrellyVencore (United States)

Discussion

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Implication

May heighten postdischarge burden after orthopedic surgery; extends observational cost data but leaves causal prevention effects open.

Study Design

Type

Cohort (n=32,899)

Structured PICO

Does the development of DVT following major orthopedic surgery increase healthcare costs and resource utilization in adult patients?

P
Population
32,899 patients aged ≥18 years with a record of major orthopedic surgery, followed for 6 months post-discharge to assess the impact of incident DVT on healthcare utilization and costs.
E
Exposure
Development of deep vein thrombosis (DVT) during the first month after hospital discharge
C
Comparator
No development of DVT during the first month after hospital discharge
O
Outcome
Impact of DVT on total 6-month costs and resource utilization (readmissions, outpatient, emergency department visits)

The development of DVT following major orthopedic surgery is associated with significantly increased healthcare resource utilization and costs over a 6-month postdischarge period.

Cite This Study

Nutescu et al. (2008) conducted a cohort in Major orthopedic surgery (n=32,899). Deep vein thrombosis (DVT) during the first month after hospital discharge vs. No DVT during the first month after hospital discharge was evaluated on Total 6-month costs and resource utilization (readmissions, outpatient, emergency department visits). Development of DVT within one month after major orthopedic surgery was associated with a 22% and 74% increase in outpatient and emergency department visits, respectively, and over $2000 in added costs.

synapsesocial.com/papers/6a9424131e998d99dafeebc7https://doi.org/10.1345/aph.1l135
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Economic Consequences of Venous Thromboembolism Following Major Orthopedic Surgery2004 · 56 citations
  2. 2Direct Medical Costs of Venous Thromboembolism and Subsequent Hospital Readmission Rates: An Administrative Claims Analysis From 30 Managed Care Organizations2007 · 332 citations
  3. 3Postthrombotic Syndrome After Hip or Knee Arthroplasty2000 · 155 citations
  4. 4Short-Duration Prophylaxis Against Venous Thromboembolism After Total Hip or Knee Replacement2002 · 189 citations
  5. 5Prevention of Deep-Vein Thrombosis after Total Hip Arthroplasty1997 · 172 citations