Key result
Systematic inflammatory activity peaked at 24 to 48 hours after aneurysmal subarachnoid hemorrhage, and participants with higher clinical severity had elevated levels of several cytokines.
Population
45 participants with aneurysmal subarachnoid hemorrhage (aSAH)
Design
Cohort
Follow-up
6 to 8 days
Authors
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Peak systemic inflammation at 24-48 hours after aSAH was associated with severity; hypothesis-generating for timed immunomodulation trials.
Observational (n=45)
Network modeling of peripheral inflammation after aneurysmal subarachnoid hemorrhage reveals a peak in systematic inflammatory activity at 24-48 hours and correlates with clinical severity.
Savarraj et al. (2017) conducted an observational in Aneurysmal subarachnoid hemorrhage (aSAH) (n=45). Aneurysmal subarachnoid hemorrhage (aSAH) was evaluated on Systematic inflammatory activity and cytokine levels. Systematic inflammatory activity peaked at 24 to 48 hours after aneurysmal subarachnoid hemorrhage, and participants with higher clinical severity had elevated levels of several cytokines.
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