Why the study?
Does Angiotensin 1-7 improve endothelial function in mice with diet-induced obesity?
Population
Mice with diet-induced obesity (DIO) and mice with Angiotensin II-induced endothelial dysfunction
Comparison
Angiotensin 1-7 delivered subcutaneously for 4… vs Untreated DIO mice and mice treated with Ang II…
Design
Preclinical
Follow-up
4 weeks
Authors
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Ang 1-7 may benefit endothelial function in obesity; extends preclinical data but leaves open human translation.
Does Angiotensin 1-7 improve endothelial function in mice with diet-induced obesity?
Angiotensin 1-7 improves obesity-associated endothelial dysfunction and reduces oxidative stress in a preclinical mouse model.
Beyer et al. (2013) studied this question.
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