Why the study?
Does angiotensin (1-7) treatment reduce atherosclerotic lesion progression and improve endothelial function in ApoE-/- mice on a high-fat diet?
Does angiotensin (1-7) treatment reduce atherosclerotic lesion progression and improve endothelial function in ApoE-/- mice on a high-fat diet?
Angiotensin (1-7) demonstrates vasoprotective and atheroprotective effects in ApoE-/- mice, suggesting a potential therapeutic pathway for atherosclerosis.
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Should not change clinical practice; leaves open Ang (1-7) translation to human atherosclerosis.
Tesanovic et al. (2010) studied this question.
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