Key result
Influenza A virus genomic RNA segments are selected and packaged as an organized supramolecular complex held together by direct base pairing of packaging signals.
Population
Influenza A virus genomic RNA segments and viral ribonucleoproteins (vRNPs)
Design
Preclinical
Authors
Loading...
May inform antiviral design targeting RNA packaging; leaves open therapeutic disruption in mammalian models.
The study provides structural and biochemical evidence that influenza A virus genomic RNA segments are selected and packaged as an organized supramolecular complex held together by direct base pairing.
Fournier et al. (2011) studied Influenza A virus. Influenza A virus genomic RNA segments are selected and packaged as an organized supramolecular complex held together by direct base pairing of packaging signals.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: