Use of Medium Chain Triglycerides in Malabsorption

Article1 April 1967Use of Medium Chain Triglycerides in MalabsorptionNORTON J. GREENBERGER, M.D., RICHARD D. RUPPERT, M.D., MANUEL TZAGOURNIS, M.D.NORTON J. GREENBERGER, M.D.Search for more papers by this author, RICHARD D. RUPPERT, M.D.Search for more papers by this author, MANUEL TZAGOURNIS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-66-4-727 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRecent clinical observations have indicated that triglycerides containing medium chain fatty acids may be useful in decreasing the steatorrhea associated with a variety of malabsorptive disorders. It has been demonstrated that medium chain triglycerides (MCT) are of value in treating patients with pancreatic insufficiency (1), extrahepatic biliary tract obstruction (2), postgastrectomy steatorrhea (3), a-beta-lipoproteinemia (4), intestinal lymphangiectasia (5), cystic fibrosis of the pancreas (6), and massive small-bowel resection (7). Although it has been well documented that therapy with MCT results in decreased steatorrhea, there is little evidence available correlating decreased steatorrhea with weight gain. Moreover, there is little information concerned...References1. HASHIMROHOLTVAN ITALLIE SAHBTB: Pancreatogenous steatorrhea treated with medium chain triglycerides (abstract). Clin. Res. 10: 394, 1962. Google Scholar2. IBERHARDOONSPRAGUE FLEMH: Use of eight and ten carbon fatty acids as neutral fat in the management of steatorrhea (abstract). Clin. Res. 11: 185, 1963. Google Scholar3. 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HOLTHASHIMVAN ITALLIE PRSATB: Treatment of malabsorption syndrome and exudative enteropathy with synthetic medium chain triglycerides. Amer. J. Gastroent. 43: 549, 1965. MedlineGoogle Scholar31. ZURIERHASHIMVAN ITALLIE RBSATB: Effect of medium chain triglyceride on cholestyramine-induced steatorrhea in man. Gastroenterology 49: 490, 1965. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: NORTON J. GREENBERGER, M.D.; RICHARD D. RUPPERT, M.D.; MANUEL TZAGOURNIS, M.D.Affiliations: Columbus, OhioFrom the Division of Gastroenterology, Department of Medicine, Ohio State University College of Medicine, Columbus, Ohio.This study was supported in part by grant FR-34, U. S. Public Health Service, Washington, D. C.Requests for reprints should be addressed to Norton J. Greenberger, M.D., Department of Medicine, Ohio State University Hospital, 410 W. 10th Ave., Columbus, Ohio 43210. 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