Key result
Animal models of arterial aneurysm, including a novel laparoscopy-based pig model, provide important insights into early pathogenesis and the evaluation of novel device prototypes.
Animal models of arterial aneurysm provide important insights into early pathogenesis and are relevant for evaluating treatment protocols and novel device prototypes.
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Animal models may guide preclinical aneurysm device testing; leaves open human translation.
We review the results from the most common animal models of arterial aneurysm, including recent findings from our novel, laparoscopy-based pig model of abdominal aortic aneurysm, that contribute important insights into early pathogenesis. We emphasize the relevance of these findings for evaluation of treatment protocols and novel device prototypes for mechanism-based prevention of progression and rupture.
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Gertz et al. (2013) conducted a review in Arterial aneurysm. Animal models of arterial aneurysm was evaluated. Animal models of arterial aneurysm, including a novel laparoscopy-based pig model, provide important insights into early pathogenesis and the evaluation of novel device prototypes.
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