Key result
In 614 cardiac surgery patients, 46% had cerebral autoregulation limits outside the population optimal mean arterial pressure of 78 mmHg, highlighting the potential need for individualized blood pressure targets during cardiopulmonary bypass.
Why the study?
Does tailoring blood pressure targets to individual cerebral autoregulation limits prevent postoperative stroke in cardiac surgery patients undergoing cardiopulmonary bypass?
Population
614 cardiac surgery patients undergoing cardiopulmonary bypass (CPB)
Comparison
Tailoring blood pressure targets to a patient's… vs One-size-fits-all approach of aiming for a mean…
Design
Editorial
Authors
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Tailoring blood pressure targets to a patient's individual limits of cerebral autoregulation during cardiopulmonary bypass may be necessary to avoid severe postoperative complications, as a one-size-fits-all MAP target is inappropriate for nearly half of patients.
Does tailoring blood pressure targets to individual cerebral autoregulation limits prevent postoperative stroke in cardiac surgery patients undergoing cardiopulmonary bypass?
Tailoring blood pressure targets to a patient's individual limits of cerebral autoregulation during cardiopulmonary bypass may be necessary to avoid severe postoperative complications, as a one-size-fits-all MAP target is inappropriate for nearly half of patients.
Denault et al. (2018) conducted an editorial in Cardiac surgery requiring cardiopulmonary bypass (n=614). Individualized mean arterial pressure targeting based on cerebral autoregulation vs. Standard one-size-fits-all MAP target (e.g., 78 mmHg) was evaluated on Proportion of patients with cerebral autoregulation limits outside the population optimal MAP. In 614 cardiac surgery patients, 46% had cerebral autoregulation limits outside the population optimal mean arterial pressure of 78 mmHg, highlighting the potential need for individualized blood pressure targets during cardiopulmonary bypass.
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