Key result
At 50% in vitro hemodilution, balanced and saline-based rapidly degradable HES solutions resulted in identical ADP-induced aggregometry values (356 ± 117 AU).
Population
Whole blood obtained from 10 male volunteers (in the critiqued in vitro study)
Comparison
Balanced, plasma adapted rapidly degradable… vs Saline-based rapidly degradable HES solution
Design
Editorial
Authors
Loading...
In vitro experiments comparing balanced and saline-based HES solutions may lack clinical relevance due to the absence of physiological compensatory mechanisms and unrealistic hemodilution levels.
Absolute Event Rate: 356% vs 356%
In vitro experiments comparing balanced and saline-based HES solutions may lack clinical relevance due to the absence of physiological compensatory mechanisms and unrealistic hemodilution levels.
Scharbert et al. (2007) conducted a letter in In vitro hemodilution (n=10). Balanced rapidly degradable hydroxyethyl starch (HES) solution vs. Saline-based rapidly degradable HES solution was evaluated on ADP-induced aggregometry at 50% hemodilution. At 50% in vitro hemodilution, balanced and saline-based rapidly degradable HES solutions resulted in identical ADP-induced aggregometry values (356 ± 117 AU).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: