Why the study?
Does oral polio vaccine (OPV) compared to inactivated polio vaccine (IPV) increase the risk of paralytic disease in vaccinees?
Population
Vaccinees
Comparison
Oral polio vaccine (OPV) vs Inactivated polio vaccine (IPV)
Design
Review
Authors
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Supports preferring IPV where polio risk is low; leaves open whether VAPP justifies global policy reversion.
Does oral polio vaccine (OPV) compared to inactivated polio vaccine (IPV) increase the risk of paralytic disease in vaccinees?
The paper questions whether the risk of vaccine-induced paralytic disease from OPV justifies a return to IPV.
Vincent A. Fulginiti (1980) studied this question.