Why the study?
Does combined epidural and general anesthesia improve renal function and endocrine responses during infrarenal abdominal aortic aneurysmectomy compared to general anesthesia alone?
Does combined epidural and general anesthesia improve renal function and endocrine responses during infrarenal abdominal aortic aneurysmectomy compared to general anesthesia alone?
Combined epidural and general anesthesia during abdominal aortic aneurysmectomy provides stable hemodynamics and suppresses catecholamine/renin responses, but causes excessive vasopressin secretion without compromising renal function.
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No renal impairment despite high vasopressin with epidural anesthesia in AAA repair; hypothesis-generating and should not yet change practice.
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Kono et al. (1992) studied this question.
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