Key result
Epidural ropivacaine and dexmedetomidine improves patient satisfaction and reduces nausea, vomiting, and shivering vs general anesthesia.
Why the study?
Neuraxial anaesthesia has become popular for renal surgeries, but comparative data with general anaesthesia are needed.
Does epidural anaesthesia with ropivacaine and dexmedetomidine improve outcomes compared to general anaesthesia in patients undergoing renal surgeries?
RCT (n=100)
Does epidural anaesthesia with ropivacaine and dexmedetomidine improve outcomes compared to general anaesthesia in patients undergoing renal surgeries?
Epidural anaesthesia with ropivacaine and dexmedetomidine is a safe and effective alternative to general anaesthesia for renal surgeries, offering better patient satisfaction and fewer post-operative side effects like nausea and shivering.
Supports epidural anaesthesia with ropivacaine and dexmedetomidine for renal surgeries; extends RCT evidence favoring regional over general anaesthesia.
BACKGROUND AND AIMS: Neuraxial anaesthesia has become popular for the renal surgeries during the last few years. This study was aimed at comparing general anaesthesia (GA) with epidural anaesthesia in patients undergoing renal surgeries. METHODS: One hundred American Society of Anaesthesiologists (ASA) physical status-I and II adult consenting patients of both gender in the age group of 25-55 years undergoing renal surgeries were randomly assigned to two groups of 50 patients each: Group G and Group E. Group G patients were administered conventional GA while Group E received epidural anaesthesia (EA) with 3 mg/kg of ropivacaine and 1 μg/kg of dexmedetomidine. Besides cardio-respiratory parameters, surgeon's satisfaction, patient's satisfaction and side effects were observed. Parametric data were analysed by ANOVA while non-parametric data were compared with Mann-Whitney U-test and Wilcoxon test. Value of P < 0.05 was considered statistically significant. RESULTS: The demographic profile, total anaesthesia time, surgical time and haemodynamic parameters and surgeon's satisfaction scores were comparable in both groups. Patient's satisfaction scores were better in Group E during the post-operative period. Incidence of side-effects such as nausea and vomiting and shivering were higher in Group G (P < 0.001) while the incidence of dry mouth was higher in Group E (P < 0.001). CONCLUSION: Epidural anaesthesia with ropivacaine and dexmedetomidine can be safely and effectively used in patients undergoing renal surgeries.
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Bajwa et al. (2014) conducted an RCT in Renal surgeries (n=100). Epidural anaesthesia vs. General anaesthesia was evaluated on Cardio-respiratory parameters, surgeon's satisfaction, patient's satisfaction and side effects. Epidural anaesthesia with ropivacaine and dexmedetomidine improved postoperative patient satisfaction and reduced nausea, vomiting, and shivering compared to general anaesthesia (P<0.001).
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