Why the study?
Does a 72-hour continuous infusion of dobutamine improve functional class, exercise time, and cardiac function in patients with severe congestive heart failure?
Population
15 patients with congestive cardiomyopathy manifested by heart failure
Comparison
Dobutamine infused continuously for 72 hours… vs 5% dextrose in water infused continuously for 72…
Design
RCT, Randomly assigned
Follow-up
4 weeks
Authors
Loading...
Supports short-term dobutamine infusion for sustained gains in severe HF; extends evidence for intermittent inotrope therapy.
Does a 72-hour continuous infusion of dobutamine improve functional class, exercise time, and cardiac function in patients with severe congestive heart failure?
A 72-hour continuous infusion of dobutamine in patients with severe congestive heart failure produced sustained improvements in functional class, exercise capacity, and left ventricular ejection fraction up to 4 weeks.
Liang et al. (1984) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: