A clinical case of the use of a closed loop system in the treatment of type 1 diabetes mellitus

The urgency of the problem of type 1 diabetes mellitus (T1DM) does not lose ground over time due to the peculiarities of the course of the disease, the need for radical lifestyle correction, which leads to a decrease in the quality of life of patients, as well as a high probability of early disability and mortality of patients at a young age. Unsatisfactory glycemic control in T1DM is closely interrelated with both the risk of rapid development of chronic complications and the likelihood of acute complications. Achieving optimal glycemic control during insulin therapy requires frequent monitoring of glycemia, a detailed understanding of the rules for counting bread units, the ability to recognize and stop hypoglycemia at early stages, as well as the ability to adapt the administration of insulin to various life situations. With the advent of pump insulin therapy, some of these factors stopped to cause inconvenience to patients, however, even with pump insulin therapy, patients still need frequent monitoring of glycemia, self-administration of bolus insulin with counting bread units, as well as correction of insulin administration manually if necessary. The use of a closed loop system is highly promising in terms of improving the quality of life of patients with T1DM. This project is a semblance of a healthy pancreas. The goal is to maintain normoglycemia or blood glucose levels in a set range by automatically adjusting the basal and bolus insulin secretion rates using a pump. The adjustment of insulin secretion by the pump is carried out in accordance with the indications of the continuous glucose monitoring system. We present a clinical case of using this system by a patient with T1DM.