Key result
Among women with bicuspid aortic valve and early-onset complications, 23% experienced cardiovascular complications during pregnancy, including an 18% prevalence of hypertensive diseases of pregnancy.
Why the study?
Current peripartum guidelines for bicuspid aortic valve are extrapolated from other heritable thoracic aortic diseases and do not account for unique characteristics of these patients.
Observational (n=44)
No
Women with early-onset complications of bicuspid aortic valve disease have a high rate of peripartum cardiovascular complications, particularly hypertensive disorders, yet rarely receive guideline-recommended imaging surveillance.
Answers are grounded in this paper and cite their sources.
High peripartum complication rates with infrequent imaging in early-onset BAV; leaves open whether enhanced surveillance improves outcomes.
Bicuspid aortic valve is the most common congenital heart malformation and predisposes patients to thoracic aortic aneurysms and aortic dissections. Current peripartum guidelines are extrapolated from other heritable causes of thoracic aortic disease and do not account for unique characteristics of bicuspid aortic valve patients. We therefore evaluated the prevalence of maternal and fetal complications of women with early-onset complications of bicuspid aortic valve disease in the UTHealth Bicuspid Aortic Valve Research Registry. We found that the rate of cardiovascular complications was high and that relatively few women received guideline-recommended care.
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Truly et al. (2022) conducted an observational in Bicuspid aortic valve with early-onset complications (n=44). Pregnancy in women with bicuspid aortic valve and early-onset complications vs. General population (historical rates) was evaluated on Maternal cardiovascular complications during pregnancy. Among women with bicuspid aortic valve and early-onset complications, 23% experienced cardiovascular complications during pregnancy, including an 18% prevalence of hypertensive diseases of pregnancy.
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