Key result
Enterovirus was detected in respiratory tract or lung samples in 53.8% of SUDI infants with signs of viral infection, compared to 0% in those without such signs.
Why the study?
Is enterovirus infection associated with sudden unexplained deaths in infants who have clinical, biologic, or histologic signs of viral infection?
Population
24 sudden unexplained deaths in infants cases, divided into Group I and Group II
Comparison
Enterovirus detection using nested PCR and IgM… vs Group I versus Group II
Design
Cross-sectional
Authors
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Enterovirus may contribute to select SUDI cases with viral signs; leaves open causality and requires prospective confirmation.
Observational (n=24)
Is enterovirus infection associated with sudden unexplained deaths in infants who have clinical, biologic, or histologic signs of viral infection?
Absolute Event Rate: 53.8% vs 0%
Enterovirus infection may be specifically associated with a subgroup of sudden unexplained deaths in infants presenting with signs of viral infection.
Grangeot‐Keros et al. (1996) conducted an observational in Sudden unexpected deaths in infants (SUDI) (n=24). Enterovirus (EV) infection vs. SUDI cases without signs of viral infection was evaluated on Detection of enterovirus in respiratory tract and/or lung samples. Enterovirus was detected in respiratory tract or lung samples in 53.8% of SUDI infants with signs of viral infection, compared to 0% in those without such signs.
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