Key result
A novel plasmid-based reverse genetics system allowed the recovery of infectious influenza virus entirely from cloned DNA, enabling comprehensive genetic manipulation of negative-strand RNA viruses.
May advance influenza virology tools; leaves open clinical translation pending in vivo studies.
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
No takes yet. Share an insight, caveat, or question.
Pekosz et al. (1999) conducted an editorial in Negative-strand RNA viruses (Influenza). Plasmid-based reverse genetics system was evaluated. A novel plasmid-based reverse genetics system allowed the recovery of infectious influenza virus entirely from cloned DNA, enabling comprehensive genetic manipulation of negative-strand RNA viruses.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: