Key result
A modest reduction in salt intake from 9.7 to 6.5 g/day significantly increased basal skin capillary density at the dorsum of the fingers from 101 to 106 capillaries/mm2 (P<0.001).
Why the study?
Does a modest reduction in salt intake improve skin capillary rarefaction in individuals with untreated mild hypertension?
Population
169 individuals with untreated mildly raised blood pressure
Comparison
Modest reduction in salt intake for 12 weeks vs Higher salt intake in a crossover design
Design
RCT, randomized, double-blind
Follow-up
12 weeks
Authors
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Supports modest salt reduction to improve capillary rarefaction in mild hypertension; extends evidence for microvascular benefits beyond BP reduction.
RCT (n=169)
Double-blind
crossover
Does a modest reduction in salt intake improve skin capillary rarefaction in individuals with untreated mild hypertension?
p-value: p=<0.001
Modest salt reduction significantly improves functional and structural capillary rarefaction in individuals with mild hypertension across different ethnic groups.
He et al. (2010) conducted an RCT in mild hypertension (n=169). Modest reduction in salt intake vs. 9.7 g/day was evaluated on skin capillary density at the dorsum and side of the fingers (p=<0.001). A modest reduction in salt intake from 9.7 to 6.5 g/day significantly increased basal skin capillary density at the dorsum of the fingers from 101 to 106 capillaries/mm2 (P<0.001).
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