Key result
The complex pathophysiology of neonates with congenital heart disease can be simplified into seven basic subtypes to guide preoperative hemodynamic assessment and therapeutic strategies.
Why the study?
The clinical spectrum of neonates with congenital heart disease is wide and complex, requiring an in-depth understanding of physiology to assess hemodynamics and guide preoperative management.
This review provides a simplified framework of seven basic pathophysiologic subtypes to guide the preoperative hemodynamic assessment and management of neonates with congenital heart disease.
Answers are grounded in this paper and cite their sources.
May simplify preoperative hemodynamic assessment in neonates with CHD; extends prior reviews by unifying pathophysiology into seven subtypes.
PURPOSE OF REVIEW: To review preoperative assessment and management of neonates with congenital heart disease (CHD). RECENT FINDINGS: The spectrum for neonates with CHD can be wide and complex. An in-depth understanding of their physiology is the first step in assessing their hemodynamics and developing an effective therapeutic strategy. SUMMARY: There is significant heterogeneity in the anatomy and physiology in newborns with CHD. Their complex pathophysiology can be simplified into seven basic subtypes, which include systolic dysfunction, diastolic dysfunction, excessive pulmonary blood flow, obstructed pulmonary blood flow, obstructed systemic blood flow, transposition physiology, and single ventricle physiology. It is important to note these physiologies are not mutually exclusive, and this review summarizes the hemodynamic and therapeutic strategies available for the preoperative neonate with CHD.
No takes yet. Share an insight, caveat, or question.
Kohbodi et al. (2023) conducted a review in Congenital heart disease. Preoperative assessment and management was evaluated. The complex pathophysiology of neonates with congenital heart disease can be simplified into seven basic subtypes to guide preoperative hemodynamic assessment and therapeutic strategies.
Synapse has enriched 10 related papers. Consider them for comparative context: