Key result
This review serves as a primer focusing on the hemodynamics and therapeutic strategies for the preoperative neonate with congenital heart disease.
Why the study?
Clinicians caring for neonates with congenital heart disease face challenges due to significant pathophysiologic heterogeneity, requiring personalized management as infants await surgery or evaluation for further interventions.
This review provides a primer on the hemodynamics and personalized therapeutic strategies for the preoperative management of neonates with various forms of congenital heart disease.
Answers are grounded in this paper and cite their sources.
May guide preoperative neonatal CHD management; leaves open prospective validation of personalized strategies.
Clinicians caring for neonates with congenital heart disease encounter challenges in clinical care as these infants await surgery or are evaluated for further potential interventions. The newborn with heart disease can present with significant pathophysiologic heterogeneity and therefore requires a personalized therapeutic management plan. However, this complex field of neonatal-cardiac hemodynamics can be simplified. We explore some of these clinical quandaries and include specific sections reviewing the anatomic challenges in these patients. We propose this to serve as a primer focusing on the hemodynamics and therapeutic strategies for the preoperative neonate with systolic dysfunction, diastolic dysfunction, excessive pulmonary blood flow, obstructed pulmonary blood flow, obstructed systemic blood flow, transposition physiology, and single ventricle physiology.
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Ashrafi et al. (2022) conducted a review in Congenital heart disease. Preoperative management and therapeutic strategies was evaluated. This review serves as a primer focusing on the hemodynamics and therapeutic strategies for the preoperative neonate with congenital heart disease.
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