Key result
Infusion of phosphoenolpyruvate and adenosine triphosphate early during reperfusion significantly increased energy content and left ventricular isovolumic performance in a rat heart model.
Why the study?
Does supplementation with phosphoenolpyruvate and adenosine triphosphate improve myocardial energy content and left ventricular performance in a postischemic rat heart model?
Does supplementation with phosphoenolpyruvate and adenosine triphosphate improve myocardial energy content and left ventricular performance in a postischemic rat heart model?
Early reperfusion supplementation with phosphoenolpyruvate and ATP improves left ventricular performance and reduces cellular damage in a postischemic rat heart model.
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May support metabolic support in experimental reperfusion; leaves open translation to clinical myocardial protection.
Hultman et al. (2008) studied Postischemic reperfusion. Phosphoenolpyruvate and adenosine triphosphate vs. Plain saline was evaluated on Energy content and left ventricular isovolumic performance. Infusion of phosphoenolpyruvate and adenosine triphosphate early during reperfusion significantly increased energy content and left ventricular isovolumic performance in a rat heart model.
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