Key result
Recombinant hirudin provided safe and effective anticoagulation in three patients with HIT II undergoing cardiovascular surgery without cardiopulmonary bypass, with no thromboembolic complications.
Population
3 patients with Heparin-Induced Thrombocytopenia Type II requiring cardiac or vascular surgery without…
Design
Case_series
Authors
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May support hirudin in select HIT II off-pump cases; hypothesis-generating and should not yet change practice.
Case Report (n=3)
Recombinant hirudin provides a potential alternative for anticoagulation in patients with HIT II undergoing cardiovascular surgery without cardiopulmonary bypass.
Koster et al. (2000) conducted a case report in Heparin-Induced Thrombocytopenia Type II (HIT II) (n=3). Recombinant hirudin was evaluated on Thromboembolic complications and bleeding. Recombinant hirudin provided safe and effective anticoagulation in three patients with HIT II undergoing cardiovascular surgery without cardiopulmonary bypass, with no thromboembolic complications.
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