Key result
EMMPRIN is expressed in human endometrium during the menstrual cycle, and its production and glycosylation are augmented by progesterone.
Population
Human endometrium tissue and primary cultured endometrial stromal and glandular epithelial cells
Design
Preclinical
Authors
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May inform endometrial remodeling mechanisms; leaves open EMMPRIN's role in reproductive disorders pending clinical studies.
EMMPRIN is expressed in the human endometrium in a menstrual cycle-dependent manner and is regulated by progesterone, suggesting a role in extracellular matrix breakdown.
Noguchi et al. (2003) studied Menstrual cycle. Menstrual cycle phases and progesterone was evaluated on EMMPRIN expression and glycosylation. EMMPRIN is expressed in human endometrium during the menstrual cycle, and its production and glycosylation are augmented by progesterone.
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