Key result
Low serum vitamin D levels were significantly associated with higher rates of hypertensive complications, including retinopathy (p=0.014), left ventricular hypertrophy (p=0.0004), and nephropathy (p=0.000017).
Why the study?
Recent studies support an association between low serum vitamin D levels and hypertension pathogenesis, prompting estimation of vitamin D levels in hypertension and related complications.
Observational (n=100)
No
p-value: p=0.000017
Low serum vitamin D levels are highly prevalent in patients with essential hypertension and significantly correlate with the presence of target organ damage such as retinopathy, nephropathy, and left ventricular hypertrophy.
Hypothesis-generating for vitamin D assessment in hypertension; prospective trials needed before any practice change.
Background: India with population of around 1.38 billion harbours nearly 200 million1 hypertension patients. Hypertension is an important non-communicable disease with multifactorial biological aspects for its pathogenesis. Many recent analytical studies supported the evidence of low serum vitamin D level in pathogenesis of hypertension. Our objective was to estimate serum vitamin D level in patients with hypertension and hypertension related complications.Aims & Objectives: 1. To estimate serum Vitamin D level in Essential Hypertension and Hypertension related complications. 2. To establish the relationship between serum Vitamin D level and Hypertension and hypertension related complications.Materials & Methods:Design: Hospital based Observational studyPlace of Study: Department of General MedicineStudy Population: Cases attending RMMCH OPD during the study period will be screened for hypertension and hypertension related complications.Sample Size: 100Results: It has been observed that in this study serum vitamin D level is low in hypertension patients and also, the lower level correlated with hypertensive complications like retinopathy, nephropathy and cardiac complications.Conclusion: The study results reveals that low serum vitamin D level is present in significant number of study populations. Also the low serum vitamin D level correlated with hypertension related complications.
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Sundareshwaran et al. (2022) conducted an observational in Hypertension and hypertension-related complications (n=100). Low serum Vitamin D level vs. Normal serum Vitamin D level (>30 ng/dl) was evaluated on Prevalence of hypertension-related complications (retinopathy, nephropathy, left ventricular hypertrophy) according to serum vitamin D levels (p=0.000017). Low serum vitamin D levels were significantly associated with higher rates of hypertensive complications, including retinopathy (p=0.014), left ventricular hypertrophy (p=0.0004), and nephropathy (p=0.000017).
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