Why the study?
Does nitrendipine alter blood pressure and calcium metabolism in essential hypertensive outpatients?
Does nitrendipine alter blood pressure and calcium metabolism in essential hypertensive outpatients?
The antihypertensive efficacy of nitrendipine is greatest among salt-sensitive and lower-renin patients, and is related to its ability to alter calcium metabolism.
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May support preferential nitrendipine response in salt-sensitive hypertension; hypothesis-generating and requires randomized confirmation before guiding therapy.
Resnick et al. (1988) studied this question.
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