Key result
Clinical evaluation of short stature should assess both growth hormone secretion and responsiveness, as new genetic defects in growth regulation molecules have been identified.
Highlights the need to evaluate both growth hormone secretion and responsiveness in short children, rather than just immunoreactive GH levels.
No takes yet. Share an insight, caveat, or question.
May prompt dual GH secretion-responsiveness testing in short stature; leaves open standardized genetic integration into guidelines.
Boguszewski et al. (2009) conducted a review in Short stature in non-growth-hormone deficient children. Clinical evaluation of short stature should assess both growth hormone secretion and responsiveness, as new genetic defects in growth regulation molecules have been identified.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: