Why the study?
How does enzyme-linked immunosorbent assay (ELISA) compare with neutralization tests for the evaluation of antibody levels after live mumps vaccination?
Population
Individuals vaccinated with live mumps vaccines
Comparison
Enzyme-linked immunosorbent assay for… vs Neutralization tests
Design
Other
Authors
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ELISA may offer higher sensitivity than neutralization for post-vaccination mumps antibodies; leaves open its clinical or research utility pending validation.
How does enzyme-linked immunosorbent assay (ELISA) compare with neutralization tests for the evaluation of antibody levels after live mumps vaccination?
ELISA can detect mumps-specific antibodies in some vaccinees who appear not to seroconvert when evaluated by standard neutralization tests.
Sakata et al. (1984) studied this question.
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