Key result
Sequence analysis of 9 wild-type measles viruses isolated in Morocco during 1998-1999 revealed that all isolates belonged to genotype C2 and were closely related to recent western European isolates.
Observational (n=9)
This first molecular epidemiological study of measles in Morocco identified genotype C2 as the circulating strain, linking it to western European isolates.
Identifies C2 as Morocco's circulating measles genotype linked to Europe; leaves open the need for ongoing regional surveillance.
Sequence analysis was conducted on the hemagglutinin (H) and nucleoprotein (N) genes from nine wild-type measles viruses (MV) isolated during an outbreak that occurred in Morocco during 1998 and 1999. The sequence data showed that all the viruses were closely related to each other and were members of genotype C2. Genotype C2 has been shown to be circulating in Europe, and the sequences of the Moroccan isolates were most closely related to the sequences of recent viral isolates from western Europe. This report presents the first molecular epidemiological study of circulating wild-type measles viruses in Morocco. Knowledge of the indigenous strain of measles virus circulating in Morocco will help to describe viral transmission pathways and should contribute to efforts to evaluate the effectiveness of future vaccination campaigns.
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Alla et al. (2002) conducted an observational in Measles (n=9). Sequence analysis of hemagglutinin (H) and nucleoprotein (N) genes was evaluated on Genotype identification and phylogenetic relationship. Sequence analysis of 9 wild-type measles viruses isolated in Morocco during 1998-1999 revealed that all isolates belonged to genotype C2 and were closely related to recent western European isolates.
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