Why the study?
Does human antibody to the fusion protein of measles virus protect against fatal measles encephalitis in mice?
Does human antibody to the fusion protein of measles virus protect against fatal measles encephalitis in mice?
Human antibody to the fusion (F) protein of measles virus provides protection against fatal measles encephalitis in a mouse model.
Anti-F antibodies may protect against measles encephalitis in mice; leaves open translation to human therapy.
Absorption of a pooled human gamma globulin preparation with acetone-treated measles virus-infected cells removed all antibodies to measles virus antigens except a portion of the antibody to the fusion (F) protein. The residual anti-F antibody had hemolysis-inhibiting and virus-neutralizing activities, inhibited spread of infection through cell fusion, and was effective in protection of passively immunized mice from fatal measles encephalitis, providing evidence for the protective role of human antibody to the F protein of measles virus.
No takes yet. Share an insight, caveat, or question.
Sato et al. (1989) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: