Key result
Decreased anaerobic threshold (OR 0.55; 95% CI 0.37-0.84) and increased ventilatory equivalent for carbon dioxide (OR 1.18; 95% CI 1.05-1.33) predicted postoperative cardiac and pulmonary complications.
Why the study?
Do cardiopulmonary exercise testing measures predict postoperative complications in patients undergoing elective abdominal aortic aneurysm repair?
Cohort (n=130)
Do cardiopulmonary exercise testing measures predict postoperative complications in patients undergoing elective abdominal aortic aneurysm repair?
Odds Ratio: 0.55 (95% CI 0.37–0.84)
p-value: p=0.005
Cardiopulmonary exercise testing variables can predict specific postoperative cardiac and pulmonary complications following elective abdominal aortic aneurysm repair, aiding in risk stratification.
May aid preoperative risk stratification with CPET in elective AAA repair; leaves open prospective validation for outcome improvement.
This study aimed at assessing whether measures of aerobic fitness can predict postoperative cardiac and pulmonary complications, 30-day mortality and length of hospital stay following elective abdominal aortic aneurysm repair. We prospectively collected cardiopulmonary exercise testing data over two years for 130 patients. Upon multivariate analysis, a decreased anaerobic threshold (OR (95% CI) 0.55 (0.37-0.84); p = 0.005) and open repair (OR (95% CI) 6.99 (1.56-31.48); p = 0.011) were associated with cardiac complications. Similarly, an increased ventilatory equivalent for carbon dioxide (OR (95% CI) 1.18 (1.05-1.33); p = 0.005) and open repair (OR (95% CI) 14.29 (3.24-62.90); p < 0.001) were associated with pulmonary complications. Patients who had an endovascular repair had shorter hospital and critical care lengths of stay (p < 0.001). Measures of fitness were not associated with 30-day mortality or length of hospital stay. Cardiopulmonary exercise testing variables, therefore, seem to predict different postoperative complications following abdominal aortic aneurysm repair, which adds value to their routine use in risk stratification and optimisation of peri-operative care.
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Barakat et al. (2015) conducted a cohort in abdominal aortic aneurysm (n=130). Cardiopulmonary exercise testing measures (anaerobic threshold and ventilatory equivalent for carbon dioxide) was evaluated on postoperative cardiac complications (OR 0.55, 95% CI 0.37-0.84, p=0.005). Decreased anaerobic threshold (OR 0.55; 95% CI 0.37-0.84) and increased ventilatory equivalent for carbon dioxide (OR 1.18; 95% CI 1.05-1.33) predicted postoperative cardiac and pulmonary complications.
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