Preoperative cardiopulmonary exercise testing identified unfit patients who had significantly lower 2-year survival after elective open AAA repair compared to fit patients (55% vs 97%, P<0.001).
Cohort (n=130)
Does preoperative cardiopulmonary exercise testing predict postoperative survival in patients undergoing elective open abdominal aortic aneurysm repair?
Preoperative cardiopulmonary exercise testing effectively identifies patients at high risk of mid-term mortality following elective open abdominal aortic aneurysm repair.
Effect estimate: Absolute difference 42% (95% CI 18 to 65)
Absolute Event Rate: 55% vs 97%
p-value: p=<0.001
Abstract Background Cardiopulmonary exercise (CPX) testing measures how efficiently subjects meet increased metabolic demand. This study aimed to determine whether preoperative CPX testing predicted postoperative survival following elective abdominal aortic aneurysm (AAA) repair. Methods Some 130 patients had CPX testing before elective open AAA repair. Additional preoperative, operative and postoperative variables were recorded prospectively. Median follow-up was 35 months. The correlation of variables with survival was assessed by single and multiple regression analyses. Results CPX testing identified 30 of 130 patients who had been unfit before surgery. Two years after surgery the Kaplan–Meier survival estimate was 55 per cent for the 30 unfit patients, compared with 97 per cent for the 100 fit patients. The absolute difference in survival between these two groups at 2 years was 42 (95 per cent confidence interval 18 to 65) per cent (P 0·001). Conclusion Preoperative CPX testing, combined with simple co-morbidity scoring, identified patients unlikely to survive in the mid-term, even after successful AAA repair.
Carlisle et al. (Tue,) conducted a cohort in Abdominal aortic aneurysm (n=130). Unfit status on preoperative CPX testing vs. Fit status on preoperative CPX testing was evaluated on Survival at 2 years (Absolute difference 42%, 95% CI 18 to 65, p=<0.001). Preoperative cardiopulmonary exercise testing identified unfit patients who had significantly lower 2-year survival after elective open AAA repair compared to fit patients (55% vs 97%, P<0.001).