Key result
Cardiopulmonary exercise testing parameters predicted postoperative inotrope requirement and 30-month survival in patients assessed for abdominal aortic aneurysm repair.
Why the study?
The ability of cardiopulmonary exercise testing (CPET) to predict early and mid-term outcomes in patients undergoing abdominal aortic aneurysm repair was evaluated.
Does cardiopulmonary exercise testing predict early and late outcomes in patients with large abdominal aortic aneurysms?
Cohort (n=102)
No
Does cardiopulmonary exercise testing predict early and late outcomes in patients with large abdominal aortic aneurysms?
Answers are grounded in this paper and cite their sources.
Cardiopulmonary exercise testing parameters, specifically anaerobic threshold and ventilatory equivalents for oxygen, can predict mid-term survival and early postoperative outcomes in patients with large abdominal aortic aneurysms.
INTRODUCTION: The aim of this study was to determine if cardiopulmonary exercise testing (CPET) predicts 30-day and mid-term outcomes when assessing suitability for abdominal aortic aneurysm (AAA) repair. METHODS: Since July 2006 consecutive patients from a single centre identified with a large (≥5.5 cm) AAA were sent for CPET. Follow-up was completed on 1 August 2009. Univariate logistical regression was used to compare CPET parameters with the Detsky score, the Acute Physiology and Chronic Health Evaluation (APACHE) II score and the Vascular Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (VPOSSUM) in predicting predefined early and late outcome measures. RESULTS: Full data were available for 102 patients (93% male, median age: 75 years, interquartile range (IQR): 70-80 years, median follow up: 28 months, IQR: 18-33 months). Ventilatory equivalents for oxygen and APACHE II predicted postoperative inotrope requirement (p=0.018 and p=0.019 respectively). The Detsky score predicted the length of stay in the intensive care unit (p=0.008). Mid-term (30-month) survival was predicted by the anaerobic threshold (p=0.02). CONCLUSIONS: CPET provided the only means in this study of predicting both 30-day outcome and 30-month mortality. CPET could therefore become an increasingly important tool in determining the optimum management for AAA patients.
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Thompson et al. (2011) conducted a cohort in Abdominal aortic aneurysm (AAA) (n=102). Cardiopulmonary exercise testing (CPET) vs. Detsky score, APACHE II score, and VPOSSUM was evaluated on 30-day and mid-term outcomes (including postoperative inotrope requirement, ICU length of stay, and 30-month survival). Cardiopulmonary exercise testing parameters predicted postoperative inotrope requirement and 30-month survival in patients assessed for abdominal aortic aneurysm repair.
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