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August 29, 2011Annals of The Royal College of Surgeons of EnglandOpen Access

Cardiopulmonary exercise testing provides a predictive tool for early and late outcomes in abdominal aortic aneurysm patients

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Key result

CPET parameters predict postoperative inotrope requirement and 30-month survival in AAA repair patients.

  • n=102

Why the study?

The ability of cardiopulmonary exercise testing (CPET) to predict early and mid-term outcomes in patients undergoing abdominal aortic aneurysm repair was evaluated.

Does cardiopulmonary exercise testing predict early and late outcomes in patients with large abdominal aortic aneurysms?

Population

102 patients with large (≥5.5 cm) abdominal aortic aneurysm from a single centre

Comparison

CPET parameters compared with Detsky, APACHE II, and VPOSSUM scores

Design

Single-centre cohort study

Follow-up

Median 28 months

Authors

ATAR ThompsonNPN. A. L. R. PetersRLR E Lovegrove

Discussion

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Overview

CPET may aid perioperative risk stratification in AAA repair; leaves open its impact on patient selection or survival in prospective trials.

Study Design

Type

Cohort (n=102)

Multicenter

No

Structured PICO

Does cardiopulmonary exercise testing predict early and late outcomes in patients with large abdominal aortic aneurysms?

P
Population
102 patients (93% male, median age 75 years) with a large (≥5.5 cm) abdominal aortic aneurysm, followed for a median of 28 months.
E
Exposure
Cardiopulmonary exercise testing (CPET)
O
Outcome
30-day and mid-term (30-month) outcomes including postoperative inotrope requirement, length of stay in the intensive care unit, and mid-term survivalhard clinical

Cardiopulmonary exercise testing parameters, specifically anaerobic threshold and ventilatory equivalents for oxygen, can predict mid-term survival and early postoperative outcomes in patients with large abdominal aortic aneurysms.

Cite This Study

Thompson et al. (2011) conducted a cohort in Abdominal aortic aneurysm (AAA) (n=102). Cardiopulmonary exercise testing (CPET) vs. Detsky score, APACHE II score, and VPOSSUM was evaluated on 30-day and mid-term outcomes (including postoperative inotrope requirement, ICU length of stay, and 30-month survival). Cardiopulmonary exercise testing parameters predicted postoperative inotrope requirement (p=0.018) and 30-month survival (p=0.02) in patients assessed for abdominal aortic aneurysm repair.

synapsesocial.com/papers/6aa92f308e04063aed2554c3https://doi.org/10.1308/003588411x587235
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Epidemiological study of the relationship between volume and outcome after abdominal aortic aneurysm surgery in the UK from 2000 to 20052007 · 130 citations
  2. 2Exercise Anaerobic Threshold and Ventilatory Efficiency Identify Heart Failure Patients for High Risk of Early Death2002 · 495 citations
  3. 3Endovascular versus Open Repair of Abdominal Aortic Aneurysm2010 · 1,417 citations
  4. 4Cardiac Assessment for Patients Undergoing Noncardiac Surgery A Multifactorial Clinical Risk Index1986 · 487 citations
  5. 5POSSUM: A scoring system for surgical audit1991 · 1,729 citations