Population
Cells infected with herpes simplex virus type 1 or type 2
Comparison
51Cr release assay by antibody and complement vs Microneutralization test
Design
Preclinical
Authors
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Supports 51Cr release assay for HSV antibody research; leaves open human validation and clinical translation.
The 51Cr release assay is a reproducible method for quantitating antibodies to herpes simplex virus types 1 and 2, yielding results comparable to microneutralization tests.
McClung et al. (1976) studied this question.
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