Key result
Methadone intoxication induced polymorphic ventricular tachycardia that was complicated by Takotsubo cardiomyopathy in a 48-year-old malnourished woman.
This case report highlights the potential for methadone intoxication to induce polymorphic ventricular tachycardia leading to Takotsubo cardiomyopathy.
Methadone intoxication with polymorphic VT may trigger TC; this single case leaves open causal links and should not change practice.
Takotsubo cardiomyopathy (TC) is a syndrome characterized by acute and transient regional systolic myocardial dysfunction. TC often mimics myocardial infarction without obstructive coronary disease. We present a case of a 48-year-old woman who developed TC following the onset of polymorphic ventricular tachycardia in the setting of methadone intoxication.
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Ali et al. (2021) studied this question. Methadone intoxication induced polymorphic ventricular tachycardia that was complicated by Takotsubo cardiomyopathy in a 48-year-old malnourished woman.
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