Recognition of Helicity by Native Cyclodextrins. Highly Enantioselective Complexation of Tetrahelicene Dicarboxylic Acid with β-Cyclodextrin

This is the authors' abstract. We don't add key points for this paper.

Recognition of the helicity of 1,12-dimethylbenzo[c]-phenanthrene-5,8-dicarboxylic acid (1) by cyclodextrins (CDxs) has been studied by means of 1H NMR spectroscopy. The binding constant (K) for the (M)-1-β-CDx complex is 18700±1700 dm3 mol−1 which is much larger than that of the (P)-1-β-CDx complex (2200±100 dm3 mol−1). The results sugget the formation of the hydrogen bonds between the CO2− groups of 1 and the OH groups of twisted β-CDx in water.